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Extracellular matrix molecules are chemical signals, but, because of their size and insolubility, they act only on cell surface receptors and are neither taken up by the cells nor rapidly destroyed.
Many studies have demonstrated that the extracellular matrix molecules are potential targets for ROS, and that collagen metabolism and properties are deeply and permanently modified after irradiation, both in vitro and in vivo.
Extracellular matrix molecules are thought to be involved in guiding neuronal migration, and molecules such as NGF and GABA exert trophic effects on immature neurons.
Renal accumulation and abnormal regulation of extracellular matrix molecules are both characteristics of CKD and can be directly linked to impaired kidney function.
Observational studies involving analysis of series of cephalometric films and the behaviour of cells and extracellular matrix molecules are the methods employed in the past two decades to gain information about growth and growth factors [8].
As a consequence, matrix molecules are degraded or partially modified, soluble factors are released, and cryptic sites are exposed.
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Extrinsic self-healing can be more easily realized in commercially available polymers because no structural modification of the matrix molecules is required.
Unbound matrix molecules were removed by three washes with PBS.
Additional matrix molecules were also added to the Matrigel for aggregation assays.
Although terms of specific KEGG pathways oxidative phosphorylation and extracellular matrix molecules were commonly reported, the general GO terms reported in our global approach were identified only by some of the studies.
Type II collagen and aggrecan, typical cartilage matrix molecules, were also significantly positive.
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