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If significant changes occur in the network then the sensitivity matrix may require recalculation.
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As the problem is intrinsically difficult, the worst complexity is not changed and then some matrices may require large computation time and memory.
Negative-mode detection of neutral native glycans, in contrast, is difficult to achieve and may require specific matrices and additives [ 192].
We postulated that matrix degradation by the trophoblast podosomes may require MMP activity.
We then speculated that the stellate phenotype may require the action of matrix metalloproteinases (MMPs).
However, the correlation matrix may be required to be as close to the unit matrix as possible (optimal).
Similar to its role in hypertrophic cartilage, MMP13 present in new bone matrix may be required for the initial degradation of ECM components allowing the timely remodeling of the bone callus (Fig. 7).
As a consequence, the computation of the watermarking LUT in (5) may require a very large projection matrix (mathbb {G}).
Once the cargo has reached the peroxisomal matrix, it is released from the receptor, which may require the intraperoxisomal peripheral membrane protein Pex8 [ 2,12] or Pex14 [ 13].
2D applications may require more than 106 × 106 matrix cells, which are usually beyond the computational capacity of local clusters of computers.
Gene expression data often contain missing expression values, which may require the application of missing data estimation or imputation techniques to obtain a complete matrix of expression values.
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