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Also, mitochondrial matrix levels of superoxide may be differently regulated from cytosolic ones.
Matrix levels of succinate were not significantly changed in any of the treatment conditions (Figure 5).
Matrix levels of α-KG showed little change, with the exception of a small increase with the lowest palmitate oxidation rate (P<0.05).
The most pronounced and consistent change was a significant reduction in the matrix levels of 5 amino acids (tyrosine, tryptophan, phenylalanine, lysine, glycine) with oxidation of 19 µM palmitate.
In the case of efflux into the buffer, passive exchange of existing pools of intermediates with malate cannot explain these observations since matrix levels of intermediates were never found to decrease.
However, it is noteworthy that matrix levels of malate increased significantly in the presence of inhibitors (P<0.02; ∼300% increase) as would be expected, but also increased with 19 µM palmitate (P = 0.02; ∼30% increase) (Table S2).
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Mercury was analyzed by the cold vapor technique using the Portable Zeeman Lumex (RA-915) mercury analyzer (Ohio Lumex Co., Twinsburg, OH), with an instrument detection level of 0.2 ng/g, and a matrix level of quantification of 0.002 μg/g.
Each of the oxidizing conditions was associated with increased matrix and/or buffer levels of intermediates without a reduction in matrix levels.
Depending on whether the crystalline material is the dispersed phase or matrix, high levels of voiding or good apparent contact, respectively, can be observed.
As main components of extracellular matrix, the levels of collagen family proteins are generally up-regulated in the adipose tissue of diabetic mice [ 60].
A matrix ordered operator space is called matrix regular if, at each matrix level, the restriction of the norm to the self-adjoint elements is a regular norm.
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