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In addition, targeting of HIV-1 matrix is regulated by Gag mRNA trafficking [25].
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These data were the first to show that the properties of bone matrix are regulated, specifically through Runx2 pathway in P-AF group.
Previously, it has been shown that lumen and tube formation by ECs in collagen matrices is regulated by X2P1 integrin ECM signaling.
In these mice COL I levels were not corrected by exogenously administered plasma FXIIIA therapy, indicating that COL I matrix synthesis is regulated by cellular FXIIIA [82].
Extracellular matrix synthesis is regulated primarily by cardiac fibroblasts, more specifically, the active myofibroblast.
It is widely agreed that the matrix volume is regulated by the relative activity of the K+ channels mediating membrane potential driven potassium entry into mitochondria, and the K+/H+ antiporter catalysing proton-linked K+ extrusion activity [43,164,165,182].
Extracellular degradation of matrix proteins is regulated by MMPs produced by HSC, which in turn are regulated by several mechanisms, including gene regulation (transcription and proenzyme synthesis), cleavage of the proenzyme to an active form, and specific inhibition of activated forms by TIMPs [ 46].
Tendon integrity depends on the extracellular matrix (ECM), which is regulated by matrix metalloproteinases (MMP).
Matrix metalloproteinase activity is regulated at several levels.
Metalloproteinases are involved in the homeostasis of the extracellular matrix and expression is regulated by mechanical strain.
Translation of Mmp9 mRNA and several additional members of the family of Matrix Metalloproteinases (MMPs) is regulated by eIF4E phosphorylation in MEFs (Furic et al., 2010).
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