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For example, LIPRIN (PPFIA1), a gene known to enhance cell matrix interaction, and Contractin (CTTN), a gene implicated in squamous cell carcinoma migration and metastasis [19], [20], were both recurrently amplified in metastatic melanoma.
However, HEPACAM1 also modulates cell-extracellular matrix interaction and supports breast cancer cell spread [ 11].
Conceivably, BM continuity is the net effect of tumour matrix interaction and consequently a reflection of tumour behaviour.
Microarray analysis showed that MTAP affected the expression of genes involved in a variety of processes, including cell adhesion, extracellular matrix interaction, and cell signaling.
The benefits of 3D cell cultivation over 2D monolayers are featured due to the increased cell to cell contact, as well as cell to extracellular matrix interaction, and the accumulation of nutrients and growth factors (Saltzman et al., 1992).
It is known that both integrins and E-cadherin are associated with cancer cells characteristics through regulation of the cell-extracellular matrix interaction and homotypic cell-cell adhesion, respectively [ 33].
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Magnesium plays an important role in the body, mediating cell-extracellular matrix interactions and bone apatite structure and density.
The drug delivery applications for fibrin glue span tissue engineering to chemotherapy and involve several mechanisms for drug matrix interactions and control of release kinetics.
This novel approach eliminated the need for the repeated trypsinizations that may disrupt cell extracellular matrix interactions and impair cell viability.
Our system provides a platform for studying the role of mechanical force on the cell matrix interactions and thus finds strategies to optimize selected properties of engineered tissues.
Generally, integrin complexes mediate cell cell and cell extracellular matrix interactions and play a role in human airway epithelial proliferation.
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