Sentence examples for matrix integrity and from inspiring English sources
In particular, the unhydrated matrix resilience was selected as a parameter for optimization of the gelisphere formulation because of its large impact on drug release modulation, matrix integrity, and sensitivity to the crosslinking process.
RECK is a membrane-anchored MMP inhibitor that is implicated in the coordinated regulation of extracellular matrix integrity and angiogenesis.
RECK has been shown in studies of wound healing and cancer metastasis to be a key regulator of the extracellular matrix integrity and an inhibitor of angiogenesis [11], [17].
The HA0 decrease is associated to both structural matrix integrity and biochemical content.
This allows the long-term culture of cartilage tissue over several weeks under maintenance of matrix integrity and homoeostasis.
After 24 hours, hypoxia had a profound effect on several genes purported to play a key role in bone remodeling, matrix integrity, and the bone vasculature (Table 2).
Furthermore, we have shown that hypoxia can modulate the activity and phenotype of osteoblasts isolated from the tibia plateau bone of patients with knee OA, negatively affecting the degree of mineralized bone formation and modulating the expression of genes that mediate bone matrix integrity, bone remodeling, and bone vasculature.
The potential of these biocompatible scaffolds for tissue engineering is increased by preserving porous matrix integrity, promoting angiogenesis and reducing foreign body reactions.
Changes in cartilage matrix turnover (proteoglycan synthesis, retention and release) and matrix integrity (proteoglycan content) were determined.
As mentioned above, mechanical factors are integrally involved in cartilage matrix integrity, as well as survival and death of chondrogenic cells in native cartilage as well as repair tissues [ 157, 168, 169].
An optimum balance between degradability and mechanical properties, such as elastic modulus and matrix integrity, is vital to ensure the proper functionality of the hydrogel within the desired timespan.
