Sentence examples for matrix in tumor from inspiring English sources

This enables MSCs to migrate into tumor sites and play a role in the construction of the extracellular matrix in tumor tissues [10].

The secretion level and the type of proteoglycans impact the function of extracellular matrix in tumor to a great degree [ 1].

The complex formation of cationic vehicle and DNA may interact with the extracellular matrix materials after local gene administration (e.g., in arterial walls, vitreous of the eye, joints, dermis, extracellular matrix in tumor, etc).

Fibroblasts have a well-recognized role in the carcinogenic process as remodelers of the extracellular matrix in tumor stroma and as a source of paracrine growth factors that influence the growth of carcinoma cells [ 27, 28].

In keeping with the notion that the extracellular matrix in tumor differs from that in normal tissue [ 22] glypican-1, laminin alpha 3, tenascin C, versican, as well as different types of collagens (collagen typeI-alpha2, typeIII-alpha1, typeV-alpha1, typeXIII-alpha1 and typeXV-alpha1) and thrombospondin-2, were expressed at higher levels by HOC-EC than by HA-EC (Table 3A).

Extracellular matrixes in tumor nests contribute to resistance to various therapies by preventing the penetration of therapeutic agents including viral vectors [ 42].

Indeed, the corresponding CDKN2A product (p16 protein) was reported to act by blocking progression through the cell cycle [3], [4] and to suppress tumor invasion and metastasis by acting as an inhibitor of expression of various matrix metalloproteinases in tumor cells [6] [8].

The role of extracellular matrix genes in tumor growth has been previously noted [ 7, 8].

Decorin's biological activity is rather complex; it regulates multiple processes in the extracellular matrix and in tumor cells.

They have also been shown to play key roles in neoplastic transformation and the passage of tumor cells through the endothelial vessel wall and extracellular matrix in several tumor types, including the prostate [ 43- 47].

Naba et al. also demonstrated that both cancer cells and non-cancer cells which are also found within the tumors contributed to the production of the extracellular matrix in the tumor.