Sentence examples for matrix guidance from inspiring English sources

They can also be involved in other cellular processes such as wound healing, adhesion to the extracellular matrix, guidance toward chemoattractants, and neuronal growth-cone pathfinding[28].

To establish connections with other sprouting ECs at a distance, sprouting tip cells are believed to establish guidance pathways within the extracellular matrix through tensional forces, i.e. by creating a "matrical track" [21] or "matrix guidance pathway" [56].

Additionally, nanotopographically defined matrix guidance cues have been explored as an alternative method to structurally organize monolayers of tissues.

Concentration gradients of matrix-bound guidance cues in the extracellular matrix direct cell growth in native tissues and are of great interest for the design of biomedical scaffolds and on implant surfaces.

In contrast to migration within the endoderm, Heasman and coworkers (Heasman et al., 1981) had shown earlier that, in Xenopus laevis, fibronectin plays an important role for PGC migration via the dorsal mesentery, reflecting the contribution of the extracellular matrix to PGC guidance.

MLIF has been broadly investigated and at the moment, there is also scientific evidence on the effect of this molecule upon the expression of genes involved in angiogenesis, extracellular matrix synthesis/degradation, axonal guidance, and even those encoding for certain growth factors [ 20].

Such aligned matrices can provide guidance for neural cell migration and directional axonal regeneration, which is a key engineering target for neural repair.

In particular, targeted drug treatments, that is directed towards a specific patient groups will benefit from a predictive guidance utilizing matrix assisted laser desorption/ionization mass spectrometry imaging (MALDI-MSI).

In this study, we evaluated the effect of affinity-based delivery of GDNF from a fibrin matrix in a nerve guidance conduit on nerve regeneration in a 13 mm rat sciatic nerve defect.

We investigated how engineered gradients of exogenous growth factors, immobilized to an extracellular matrix material, influence collective guidance of stem cell populations over extended time (>1 day) and length (>1 mm) scales in vitro.

The current challenge for researchers is to develop a biomimetic scaffold that is capable of stimulating the re-growth of the native tissue, thus structurally mimicking the extracellular matrix (ECM), providing chemical guidance cues and mechanical support for re-enervation of the damaged region.