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In particular, expression of extracellular matrix genes in leiomyomata is deranged and such genes represent potential novel targets for therapy.
This file condenses the more detailed annotations listed in Supporting Information File S1, and further illustrates the prevalence of regulatory genes, development genes, signal transduction genes, and non-cuticular extracellular matrix genes, in addition to structural genes of cuticle.
The role of extracellular matrix genes in tumor growth has been previously noted [ 7, 8].
This insertion likely occurred by recombination between the hemagglutination and matrix genes in the LPAI virus.
Treatment of cells with atRA reduced mRNA levels of all three matrix genes in a concentration-dependent manner.
The expression of extracellular matrix genes in human adipose tissue is markedly modified after weight reduction (Kolehmainen et al, 2008).
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Detection of influenza A virus was done using primers targeting matrix gene in a single step RT-PCR.
This study investigated the role of the miR-17 92 miR-17 92n the aged heart, in view of its cluster role in regulathen of magedx genes and in cellular aging (Dews et al., 2006; Suarez et al., 2008; Sheartt al., 2009).
Both molecules have been previously implicated in the expression of extracellular matrix genes, which in and of themselves have been associated with metastatic progression.
We showed here that several extracellular matrix genes identified in adult muscle samples are actually expressed in fibroblasts and the same could be true for the in vitro cultured cells.
Representative images are shown in Figure 2. Chondrocyte differentiation and the expression of cartilage matrix genes are in part regulated by Sox transcription factors [ 42].
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