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Blood can also be a valuable matrix for measuring biomolecular adducts such as DNA, hemoglobin, or albumin adducts (Anwar 1997).

Ostrea and colleagues have reported that meconium is a sensitive matrix for measuring markers of gestational drug use and prenatal pesticide exposure [ 2- 6].

Meconium is a useful biological matrix for measuring prenatal tobacco smoke exposure and could be used in epidemiological studies that enroll women and infants at birth.

However, the biologic and technical factors noted above strongly support urine as the optimal matrix for measuring nonpersistent, semivolatile, hydrophilic environmental agents.

To avoid obtaining non-representative samples, assessment of adrenocortical function can be standardized using faeces as a hormone matrix for measuring time-averaged response to a stressor [ 9- 11].

We are not aware of previous studies that attempted to validate meconium as a matrix for measuring biomarkers of prenatal tobacco smoke exposure using repeated serum cotinine measures for comparison.

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Similar(51)

For each of the three constant environments (i.e. control, uranium and salt), we estimated one matrix for traits measured in hermaphrodites (i.e. total, early and late fertility, and growth) and one for traits measured in males (i.e. body bend and growth).

Figure 6 Scatter plot Matrix for luminance measured by all the sensors.

Sensor n° 8 for example, situated below a grating connecting the Carcer and the Tullanium, shows a high linear correlation (r2 = 0.9819) with point n° 6 and all Tullianum points; a significatively lower correlation with Carcer points is evidenced (r2 = 0.704 with point n° 2). Figure 7 Scatter plot Matrix for temperature measured by all the sensors.

Table  1 depicts the descriptive statistics as well as the correlation matrix for the measured variables.

The entire Spearman correlation matrix for pesticides measured in Janus is presented in Supplemental Material, Table S2.

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