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The implication is that naturally derived DOC may not be an appropriate surrogate for wastewater derived DOC as a matrix for assessing the fate of micropollutants in engineered systems.
Dried blood spots may provide a potential matrix for assessing exposure to certain PFCs.
Newborn DBS provide a convenient matrix for assessing both thyroid function and perchlorate exposure.
Weiss et al. (2005) suggested that butter was a suitable matrix for assessing POPs contamination of dairy products with POPs.
In this respect, breast milk samples may be a valuable biologic matrix for assessing long-term average exposure, not only to persistent toxicants but also to endocrine disrupters with a short half-life such as phthalates.
Urine has long been the preferred matrix for assessing human exposures to environmental chemicals because it is easy to obtain and can be collected without pain, an especially important consideration when studies include infants or children [ 89, 90].
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An important question relates to the choice of suitable biological matrices for assessing exposure during this period.
Since POPs build up in body fat, there are three primary matrices for assessing the body burdens of these chemicals: breast milk, blood, and fatty tissue.
Amniotic fluid, cord blood, and meconium are promising matrices for assessing prenatal exposures, a period when humans are highly susceptible to potential adverse health effects from exposure to certain chemicals.
We have recently shown that exhaled breath condensate (EBC), a fluid formed as a result of the cooling of expired air, is a suitable matrix not only for assessing the biomarkers of oxidative stress in exposed workers [malondialdehyde (MDA)] but also for quantifying the levels of some pneumotoxic substances in the lung, in particular, cobalt (Goldoni et al. 2004).
The value (back calculated) obtained from QC's nominal concentration were considered for assessing matrix effect whereas Post-extraction-spiking method was applied to note the matrix effects, in properly stored samples.
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