Sentence examples for matrix engineered from inspiring English sources

Furthermore, effects of insulin treatment on force of contraction and relaxation were evaluated by cardiomyocytes grown in a three-dimensional collagen matrix (engineered heart tissue, EHT) stimulated for 5 days by insulin.

The latter publication examined human fibroblasts from dermis and tendon and demonstrated the formation of fibrils with a narrow-sized diameter in a cell culture system studied 5 18 weeks after cells were embedded in a matrix engineered from polyglyconic acid.

In summary, our study demonstrates that synthetic culture matrices engineered from combinatorial polymers can be utilized to promote in vitro maturation of human iPSC-CMs through the engagement of critical matrix-integrin interactions.

To provide multipotent cells with a three-dimensional environment closer to bone matrix, an engineered construct mimicking bone components has been designed and evaluated.

To provide osteoblast cells with a three-dimensional environment closer to bone matrix, an engineered construct mimicking bone components have been designed and evaluated.

When embedded in the matrix surrounding engineered human vessels, these ccRCC tumor clusters drove potent endothelial cell sprouting under continuous flow, thus recapitulating the critical angiogenic signaling axis between human ccRCC cells and endothelial cells.

This research demonstrates that: (1) substrate stiffness directly affects in vitro tissue development and mechanical properties; (2) rigid materials likely inhibit elastin incorporation into the extracellular matrix of engineered arterial tissues; and (3) grafts with physiologic compliance and significant elastin content can be engineered in vitro after only days of cell culture.

To identify lamin A-associated genome regions, we performed chromatin immunoprecipitation (ChIP) using the Strep-Tactin matrix, an engineered streptavidin analogue for selective binding (Kd = 1 μM) to the OST tag (Junttila et al. 2005; ESM Fig.  S2a).

The "test-matrices" were engineered so that one particular property (e.g. low, intermediate and large intensity fluctuations and varying types of intensity gradients) was amplified so the influence of this feature could be tested.

Here we present an example for inducing local bone regeneration with a matrix-bound engineered active fragment of human parathyroid hormone (PTH1 34), linked to a transglutaminase substrate for binding to fibrin as a delivery and cell-invasion matrix with an intervening plasmin-sensitive link (TGplPTH1 34).

In order to broaden the range of matrices and implicitly to develop the class of drug delivery systems based on diffusion mechanism, in this study the starting materials, SBA-15 powder matrices, were engineered by MgO modification for antihypertensive drugs intercalation.