Sentence examples for matrix basement membrane from inspiring English sources

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Both, the proteomic data and their confirmation by immunoblotting strongly suggest that the maintenance and architecture of the extracellular matrix, basement membrane, and cytoskeletal network are severely impaired in the aged mdx heart.

For Matrigel invasion assays, Growth Factor Reduced Matrigel Matrix Basement Membrane (BD, 356230) was diluted (1 5) and added to Transwell Permeable Support invasion chambers (Corning, 3422) in 24 wells to form a thin layer.

During invasion, malignant cells reside within two major types of extracellular matrix: the basement membrane or the stromal matrix [ 28].

Adhesion to the extracellular matrix and invasion across the matrix and basement membrane are the critical steps in tumour metastasis.

EHS mouse tumors produce a homogenous interstitial matrix of basement membrane material, making EHS interstitial matrix a typical in vitro model for physiological BMs which are usually too thin for content analysis [128], [129].

Proteolysis of the extracellular matrix and basement membrane, by proteases such as matrix metalloproteinases (MMPs), is a central part of tumour growth and metastasis.

Matrix metalloproteinases (MMPs) are central to degradation of the extracellular matrix and basement membrane during both normal and carcinogenic tissue remodeling.

Previous studies have shown that enzymatic cleavage of heparin sulfate by heparinase results in disassembly of the extracellular matrix and basement membrane dissolution, inducing structural modifications that loosen the extracellular matrix barrier and enable cell invasion [ 51].

Matrix metalloproteinase 9 (MMP-9) is able to degrade the extracellular matrix and basement membrane leading to cancer cell invasion and metastasis.

Some of the extracellular matrix and membrane components that were upregulated in SAMP8 were restored by CR (i.e., proteinaceous matrix, collagen, basement membrane) (see Table S4, Supporting information).