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Matrix architecture is one the most complex item in a memory chip design.
Furthermore, it was shown that fibrillar matrix architecture is a crucial factor that allows for efficient 3D invasion.
The capacity of the adult articular chondrocyte to regenerate the normal cartilage matrix architecture is limited, however, and the damage becomes irreversible unless the destructive process is interrupted.
Reconstruction of full-thickness skin equivalents with physiologically relevant cellular and matrix architecture is gaining importance as an in vitro tool for basic research, and for the pharmaceutical, toxicological, and cosmetic industries.
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Healthy tissue is replaced by altered extracellular matrix and alveolar architecture is destroyed, which leads to decreased lung compliance, disrupted gas exchange, and ultimately respiratory failure and death.
The removal of such cellular components and antigen molecules whilst maintaining the corneal extracellular matrix components and architecture is required to generate scaffolds capable of generating functional tissue grafts suitable for transplantation.
Fibronectin (Fn), a high molecular weight glycoprotein, is a central element of extracellular matrix architecture that is involved in several fundamental cell processes.
This technique allows a flexible fabrication of interconnected porous scaffolds with compositional or morphological variation across the entire matrix, with architecture being highly reproducible.
Periostin, a matricellular protein associated with remodeling of the extracellular matrix and connective tissue architecture, is emerging in pathological conditions associated with fibrosis in adult life.
On the basis of these observations, we speculate that for a large number of quantitative traits, the S matrix built from their inferred genetic architecture is similar to the averaged G matrix.
While explants diced into small pieces accentuate cell apoptosis and matrix degradation, the large explants used here minimize cell death and enable maintenance of normal matrix metabolism; thus, native collagen architecture is retained away from the cut edges of the disks.
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