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Metzincins are key molecules in the degradation of the extracellular matrix and play an important role in cellular processes such as cell migration, adhesion, and cell fusion of malignant tumors, including cutaneous melanoma (CM).
Focal adhesions (FAs) are specialized membrane-associated multi-protein complexes that link the cell to the extracellular matrix and play crucial roles in cell-matrix sensing.
MMP-2, MMP-9, and uPA are known to be involved in the degradation of extracellular matrix and play a critical role in tumor invasion and metastasis.
MMPs are proteolytic enzymes that break down components of the extracellular matrix and play a role in cell growth and repair.
Laminin and collagen type IV are important components of the extracellular matrix, and play a role in cell adhesion and motility.
These peptides can act in the extracellular matrix and play an important role in the evolution of angiogenesis and metastatic dissemination of cancer [ 152– 152].
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I am trying to set up a dynamic clamp by importing a series of time varying stimulating currents as a matrix and playing them in VecStim.play.
Collagen is a major component of the extracellular matrix and plays a wide variety of important roles in blood clotting, healing, and tissue remodeling.
Tissue inhibitors of matrix metalloproteinases (TIMPs) regulate the breakdown of extracellular matrix components and play an important role in tissue remodelling and growth, in both physiological and pathological conditions.
Matrix metalloproteinases (MMPs) and tissue inhibitors of MMPs (TIMPs) regulate the degradation of extracellular matrix components and play important roles in the progression of select neoplastic processes.
The heparan sulfate (HS) chains of heparan sulfate proteoglycans (HSPG) are "ubiquitous" components of the cell surface and the extracellular matrix (EC) and play important roles in the physiopathology of developmental and homeostatic processes.
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