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Fibulin 2, an extracellular matrix and plasma glycoprotein, facilitates invasion and migration of breast cancer cells [46].
The ability of S. aureus to bind to extracellular matrix and plasma proteins and to host cells determines its capacity for tissue colonization.
The potential of sasC to mediate binding to the extracellular matrix and plasma proteins Fg, TSP-1, and vWf as well as to platelets was analyzed by flow cytometry.
It is thus speculated that LukS-PV signal peptide behaves like Eap (extracellular adherence protein, also known as Map and p70), an adhesin with broad binding specificity but with particular affinity for the extracellular matrix and plasma proteins, which binds to the S. aureus cell wall by a sortase-independent mechanism.
The first step involves the adherence of the bacteria to artificial surfaces that can occur either directly or via host factors acting as bridging molecules, such as the extracellular matrix and plasma proteins fibrinogen (Fg) and fibronectin (Fn) or platelets [6].
Atl participates in biofilm formation and mediates binding to the extracellular matrix and plasma proteins [ 31, 67, 68].
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In plants tissues affected by aphid attack, O 2 ·− and H2O2 are often enhanced in apoplastic as well as in symplastic regions, besides their main concentration in exocellular matrix, peroxisomes/mitochondria and plasma membrane (Smith and Boyko 2007; Maffei et al. 2007).
Interestingly, over half of the genes in the signature produce secreted proteins (20%) or proteins that are found in regions of the cell that would allow extracellular signaling, like the extracellular matrix (12%) and plasma membrane (30%).
As shown in Figure 4, in the cellular component category, six GO terms were overrepresented, they were the extracellular region, the extracellular region part, the extracellular space, the extracellular matrix, the proteinaceous extracellular matrix, and the plasma membrane part.
Neutrophil elastase (HNE) is one of the most destructive enzymes with the capability of degrading almost all extracellular matrix and key plasma proteins, and plays a crucial role in the pathophysiology of ARDS [8], [9].
Table 1 shows the averaged recovery values from surrogate matrix and human plasma for each sphingolipid class.
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