Sentence examples for matrix accumulation and from inspiring English sources
Extracellular matrix accumulation and chondrocyte gene expression in tissue-engineered cartilage constructs.
Therefore, we investigated the possible link between HA matrix accumulation and cardiac fibroblast activation in response to hyperglycemia in vitro and diet-induced insulin resistance in vivo.
Extensive matrix accumulation and concomitant increase in mechanical properties was evident over time, particularly with the presence of Y amino acid.
Previous work has shown that integrin α1-null Alport mice exhibit attenuated glomerular disease with decreased matrix accumulation and live much longer than strain-matched Alport mice.
Current approaches require extensive cell manipulation ex vivo, using exogenous growth factors to drive tissue-specific differentiation, matrix accumulation, and mechanical properties, thus limiting their potential clinical utility.
However, the presence of pathophysiologically relevant levels of IL-1 limited matrix accumulation and inhibited any increase in mechanical properties over baseline values.
Generalized arterial alterations, such as endothelial dysfunction, medial matrix accumulations, and calcifications are associated with type 2 diabetes (T2D).
After 7 days in 3D gel culture, the chondrogenic supplements (TGF-β1 and dexamethasone) significantly stimulated chondrocytic gene expression (collagen II, aggrecan, and Sox-9) and matrix accumulation (collagen II and sGAG) in RGE-modified gels, but this response was inhibited in the RGD-modified gels.
The progression of CKD (chronic kidney disease) is characterized by glomerular hypertrophy, MC (mesangial cell) proliferation, ECM (extracellular matrix) accumulation, glomerulosclerosis and ultimately ESKD (end-stage kidney disease) [ 1].
A study reported that P-PRP treatment could stimulate the vertical migration of subchondral progenitors and cartilaginous matrix accumulation, including proteoglycan and Col II [ 60].
In the present study, however, we have demonstrated that cellular protein expression and local matrix accumulation for aggrecan and type II collagen was observed within the MSCs following injection into disc tissue.
