Sentence examples for matrices that mimic from inspiring English sources

Tissue engineering technology platforms constitute a unique opportunity to integrate cells and extracellular matrix (ECM) proteins into scaffolds and matrices that mimic the natural microenvironment in vitro.

Culture of human colon fibroblasts on matrices that mimic the mechanical properties of the normal colon or the pathologically stiff colon of Crohn's disease patients demonstrated enhanced expression of ECM components and increased proliferation of fibroblasts on the stiffer matrix [ 46].

This finding reinforces the need to fabricate bioengineered matrices that mimic living tissue matrices for tissue regeneration therapy.

The in vitro 3D culture provides mammary epithelial cells with basement membrane-like matrices that mimic in vivo growth.

In fact, the original system has recently been modified to allow the use of a variety of fibroblasts, which produce self-derived 3D matrices that mimic successive stages of tumor-induced stroma progression [ 44, 45].

Ixchel Scientific has developed a 3D gel matrix that mimics the structure of human organs, so drugs can be more accurately tested.

Here, we characterize astrocyte morphology and activation in various hydrogels to assess the feasibility of developing a matrix that mimics key aspects of the native microenvironment.

Designing artificial matrices that can mimic the tissue microenvironment in vivo and regulate the appropriate differentiation of stem cells is a promising approach to therapeutic applications.

Tissue engineering also offers the opportunity to establish complex 3D cell-matrix cultures that mimic the cellular environment and thus to provide an important tool to study tissue development, remodeling, and repair.

Major limitations of this approach are the high number of cells necessary for engineering functional tissue and the lack of a matrix that will mimic the original intestine, increase cell growth and form the intestinal stem cell niche.

The fibre structure of engineered matrix that mimic the morphology of type I collagen has exhibited good biological performance for bone regeneration.