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The polymer nanocomposites (PNC) consist of epoxy matrices filled with silica nanopowder and carbon nanotubes, respectively, as well as poly (2-vinylpyridine) (P2VP) matrices loaded with silica nanoparticles.
The cylindrical PLGA matrices loaded with BMP-7 were implanted into the osteochondral defects (2 mm in diameter, 3 mm in depth) in rabbit knees.
Microporous polycaprolactone (PCL) matrices loaded with hydrophobic steroidal drugs or a hydrophilic drug – pilocarpine hydrochloride – were produced by precipitation casting using solutions of PCL in acetone.
Polyelectrolyte carrageenan (CARR) matrices loaded with oppositely charged active substance doxazosin mesylate (DM) were investigated according to their water-uptake/erosion properties, in situ complexation ability of CARR with DM, and the possibility to achieve dual drug release control.
Further, we found that single injections of alginate matrices loaded with IL-15SA and the Toll-like receptor ligand CpG or two injections of gels carrying IL-15SA alone could elicit comparable anti-tumor activity without the need for exogenous DCs.
Peritumoral injection of alginate matrices loaded with DCs and/or an interleukin-15 superagonist (IL-15SA) around 14-day established ova-expressing B16F0 murine melanoma tumors promoted immune cell accumulation in the peritumoral matrix, and matrix infiltration correlated with tumor infiltration by leukocytes.
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The latter consisted of miniaturized electrodes, which were embedded in a silicone matrix loaded with various amounts of dexamethasone.
Two alumina coatings are developed to protect tool surface in hot forging: pure γ-alumina matrix loaded with α-alumina particles and pure γ-alumina matrix loaded with h-BN particles.
This study reports the feasibility of using supercritical fluid technology to process in one step a porous matrix loaded with a pharmaceutical agent for tissue engineering purposes.
The new composite structure presented in this article is based on a polyglyconate mesh and a porous poly- dl-lactic-co-glycolic acid) matrix loaded with gentamicin developoly- dl-lactic-co-glycolicelease of antibiotics for three weeks.
To assess the false-positive rate of our analysis procedure we first performed a control experiment, in duplicate, in which both samples were incubated with an affinity matrix loaded with the immunophilin-modulating compound AP-1497, but no soluble competitor was added.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com