It is known that cells proliferate and produce extracellular matrix in response to biochemical and mechanical stimuli.
This bond, the nitrogen analog of a sulfoxide, appears to have arisen at the divergence of sponge and cnidaria, an adaptation of the extracellular matrix in response to mechanical stress in metazoan evolution.
We found that antibody neutralization of TGF-β enhanced the decrease in the tensile strength and tensile modulus of the collagen fascicles of the patellar tendon matrix in response to ex vivo fibroblast infiltration.
The concentration ratios of TCE/ cis-DCE + VC) indicaTCE/ cis-DCE increase in molar CE concentration may result from additional TCE mobilized from the rock matrix in response to the oil injection or due to desorption/diffusion.
To clarify the role of TGF-β in a tissue-cultured tendon matrix during ex vivo cellular infiltration, the present ex vivo study was conducted to test the following hypothesis that antibody neutralization of TGF-β enhances weakening of the collagen fascicles of the patellar tendon matrix in response to ex vivo fibroblast infiltration.
Our aim was to explore, using a novel physiologic magnetic resonance imaging approach, the temporospatial brain activation matrix, in response to ingestion of a lipid meal and, by use of a CCK-1 receptor antagonist, to define the role of CCK in this activation.
Here we report the design of collagen mimetic peptides (CMPs) that assemble into a highly crosslinked 3-D matrix in response to metal ion stimuli, that may be functionalized with His-tagged cargoes, such as green fluorescent protein (GFP-His8) and human epidermal growth factor (hEGF-His6).
Moreover, keratinocytes in the normal wound healing process are regulated to migrate toward the denuded area on the provisional matrix in response to specific cytokines and ECM proteins.
Akt controls a number of metabolic and survival pathway and was recently found to translocate into the mitochondria matrix in response to insulin stimulation.
In studies utilizing in vitro assays or diploid cell culture, it is difficult to visualize subnuclear structures or to understand details of the dynamic alterations of the matrix in response to alterations of gene activity.
