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Mcl-PHAs and their copolymers are suitable for a range of biomedical applications where flexible biomaterials are required, such as heart valves and other cardiovascular applications as well as matrices for controlled drug delivery.
In addition to the conceptual proof of potential applications of nanostructured PLLA matrices for controlled drug delivery, the strategy employed herein offers a new way to construct bioactive scaffolds, such as antibacterial or anti-inflammatory scaffolds, which may find broad applications for tissue regeneration and stem cells-based biotherapy.
With the aim to establish new strategies for fabricating bioactive nanostructured matrices for controlled drug delivery or potential tissue engineering, a facile and one-pot protocol was developed in this study to produce drug-loaded poly l-lactide) (poly l-lactidectures by thermally induced PLLAe separationanostructures
Silk-elastinlike protein polymers (SELPs) have been fabricated as matrices for controlled delivery of bioactive agents.
These studies indicate that genetically engineered SELP hydrogels have potential as matrices for controlled nonviral and viral gene delivery.
A range of oligosaccharide ester derivatives (OEDs) have been designed as drug delivery matrices for controlled release.
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These findings recommend further investigations of antiviral-loaded PCL matrices for controlling heterosexual transmission of HIV.
In this study, the potential of a completely amorphous shape-memory polymer matrix for controlled drug release was comprehensively characterized according to a four step general strategy which provides concepts for validating multifunctional materials for pharmaceutical applications.
It is based on the widely known principal component analysis, which is used to generate a transformation matrix for controlling the number of parameters in the canceller.
In this study, a new strategy for self-coated interfacial layer on drug-loaded mesoporous silica nanoparticles (MSNs) based on mussel-mimetic catecholamine polymer (polydopamine, PDA) layer was developed between inorganic and organic matrix for controlling drug release.
These molecules serve as an excellent starting point for producing scaffolds that mimic the properties of the extracellular matrix for controlling stem behavior both in vitro and in vivo.
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Justyna Jupowicz-Kozak
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