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The materials in a powder form were dispersed in silicone oil as well as in active matrices containing a liquid crystalline polymer.
The results demonstrated that neurotrophins, interacting with fibrin matrices containing a large molar excess of heparin relative to growth factor, enhanced neurite extension by up to 100% relative to unmodified fibrin.
In this paper we investigate the potential role of solution calorimetry measurements in aiding the formulation of swellable matrices containing a mixture of HPMC and NaCMC, an ionic cellulose derivate.
A similar behavior was reported by Bettini et al. [ 22] in erosion-controlled matrices containing a poorly soluble drug.
First, an in-house focused compound library with various substitutions of a small number of core structures comprising 6503 compounds produced a total of 6738 (single-, double- and triple-cut) matrices containing a total of 135,619 VCs.
As already observed in matrices containing a soluble drug [ 15, 22], the diffusion front followed the swelling front but with lower rate, getting to the center of the matrix in about 7 hours.
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Noticeably, N3F-derived matrices contain a background level of gelatinolytic enzymes (Figure 7B).
Both matrices contained a high fraction of reciprocal pathways (0.76 in the macaque cortex, 0.74 in the cat cortex).
The protein matrices contain a large number of proteins with different properties.
Rejecting H0 indicates that at least two matrices contain a certain amount of congruent information.
One considers a linear composite materials (CM), which consists of a homogeneous matrix containing a random set of heterogeneities.
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