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These fractions are the first supersaturated design matrices capable of estimating interaction effects.
Collagen has broad utility as gene activated matrices, capable of delivering large quantities of DNA in a direct, localized manner.
A continuum of decomposability exists based on chemical structure; however, this continuum can be altered by interactions with minerals within matrices capable of stabilising potentially labile organic matter against biological oxidation.
In the present study, we tested whether combinatorial tools such as phage display [ 43] could be used to help design next-generation matrices capable of drug delivery.
Bidirectional cross talk between the microenvironment and resident cells is termed 'dynamic reciprocity', and opportunities to generate matrices capable of this reciprocity are afforded by multiple strategies, among the most recent being the rational incorporation of degradable chemistries in hydrogel networks (Section 4) and their application in controlled microenvironments (Section 6).
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The essential factors to achieve healing are a source of cells capable of differentiating into the tissue and an extracellular matrix capable of supporting the cells.
The structural proteins of the enamel matrix must have specific protein protein interactions to produce a matrix capable of directing the highly ordered structure of the enamel crystallites.
This work establishes the potential of this fibrous scaffold as a matrix capable of delivering genes to direct and support cellular development in tissue engineering.
PLGA containing a quick-degrading porogen can be used to release two drugs while developing a porous microarchitecture for cell ingrowth with in a matrix capable of maintaining a compressive modulus applicable for soft tissue implants.
Results indicated that spider silk films are a promising protein drug delivery matrix, capable of releasing the model protein over 90 days with a release profile close to zero order kinetic.
In the first approximation poly ethylene glycol) (PEG), a hydrophilic substance employed as a matrix capable of binding compounds such as proteins or peptides and release them in a controlled fashion, was included in the formulation.
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