Based on a set of carefully designed experiments and analyses, we have concluded that variability in virtual topologies' hop-distance distributions, variability in network traffic distributions, and pattern matching between distance and traffic matrices are major factors in determining the effectiveness of optimal node assignments.
Their poor solubility in aqueous and organic solvents and limited compatibility with polymer matrices are major drawbacks, rendering these materials incapable of achieving their full potential.
While hepatocyte lipoapoptosis is a key driving force of fibrosis progression, activated hepatic stellate cells, myofibroblasts, cholangiocytes, macrophages and components of the pathological extracellular matrix are major fibrogenic effectors and thus pharmacological targets for therapies aimed at inhibition of fibrosis progression or induction of fibrosis reversal.
Coal permeability, porosity, cleat structure, adsorption/desorption of gases, in situ stress strain of coal matrix are major parameters that influence CBM production and CO2 sequestration.
An increasing amount of evidence supports the idea that proteins of the ECM (extracellular matrix) are major players in the global control of intercellular communication and integration of environmental signals.
Matrix metalloproteinases (MMP's) are important in extracellular matrix remodeling, are major effector molecules of inflammatory cells, and play a key role in many vascular diseases, including hypertension and aneurysm formation [ 7, 8].
The method produces homogeneously-dispersed CNT networks and increases the density of the Ag matrix, which are major factors in determining the mechanical performance of CNT/Ag films.
Vascular smooth muscle cell (VSMC) proliferation, migration, and extracellular matrix (ECM) synthesis are major pathologic features of chronic allograft vasculopathy.
In this respect, TNF and matrix-metalloproteases (MMPs) are major therapeutic targets since both molecules are up-regulated early [ 5]; TNF levels in CSF are related to disease severity [ 6] and TNF and MMP's contribute to brain injury during pneumococcal meningitis [ 7- 9].
Dermal substitutes and regenerative matrices are a major topic of concern for the surgeon and staff involved in the management and closure of vascular ulcers.
Since metalloproteinases, particularly members of the ADAMTS and matrix metalloproteinase (MMP) families, are major contributors to aggrecan degradation and loss in disc degeneration, MMP-3, ADAMTS-4 and ADAMTS-5 message levels were also examined, as their suppression is essential for disc repair.
