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There are five parameter to explore: the restart probability c, the jumping probability λ, the relative importance ƞ, which controls the relative importance between two types of seeds, w d and w t that weigh the drug and target similarity matrices and network based similarity measure of the drugs and proteins, respectively.
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Histopathological examination revealed partial dense collagenous matrices and networks of fine capillary-caliber blood vessels, showing infiltration of lymphocytes, plasma cells, and mast cells.
These authors suggested helpful analytic techniques such as using arrays to display the data, creating displays (matrices and networks), tabulating the frequency of different events, ordering the information, using cross tabulations to examine the relationships between variables, and other such techniques to facilitate analysis [ 60, 80, 84, 86].
Figure 1: Matrix and network representations of the document-entity matrix.
Figure 1 : Matrix and network representations of the document-entity matrix.
The PAGER web interface provides four basic features: basic search, advanced search, matrix and network view, and data download.
A sample of metagenomic matrix and network were illustrated in Figure 1 and the similarity matrices of all datasets were shown in Additional file 2: Table S1.
Phylogenetic networks were constructed for aligned concatenated gene sequences using the NeighborNet algorithm [ 35] on the Nei Li pairwise distance matrix, and network diagrams were produced using the program SplitsTree4 [ 36].
Finally, using the HTR-8/SVneo trophoblast cell line, we demonstrated that CTGF promotes key processes involved in spiral artery remodelling, including trophoblast adhesion to extracellular matrix, and network formation.
If given a set of indicator matrices and a network visualized with Cytoscape, KeyPathwayMiner combines the data and detects maximal aberrant sub-networks and visualizes them in Cytoscape.
The norm-bounded parameter uncertainties enter into all the system matrices, and the network output is of a general type that contains both linear and nonlinear parts.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com