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However, in a male rat fertility study with JNJ-26489112, a CNS-active agent, while there were no effects on histological endpoints, mating performance or pregnancy outcomes, sperm assessment was included.
Like CgA-ko mice [11], CgB-ko animals are viable and fertile, and showed no obvious phenotype with respect to weight, mating performance and overall behavior.
Both the test drugs exhibited more increament of mating performance in mice in comparison with the increased sexual motivation.
Mounting behaviour, mating performance, and general short term toxicity of the test drugs were determined and compared with the standard drug Penegra (Sildenafil citrate).
The sexual performance as assessed by determining parameters such as penile erection, mating performance, and sexual and orientation behavior was significantly improved.
If there were any differences in effort related to mating performance between male and female, we would expect to find corresponding sex differences in body condition.
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I found that solitary males were more active during subsequent courtship displays than paired males, suggesting the detrimental effect of mating on courtship performance.
Patterns of post-mating performance supported either a level of extrinsic isolation mechanism, where backcross progeny with a higher proportion of the pathogen genome adapted to the particular host environment were favored, or an infection advantage attributed to greater genetic contribution to the hybrid from the M. lychnidis-dioicae genome.
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