The Piccolipiù study plans to recruit and follow-up a birth cohort of 3000 children born in selected maternal units located in five Italian cities (Florence, Rome, Trieste, Turin, and Viareggio).
Briefly, pregnant women aged 18 years or above who had their first trimester antenatal dating ultrasound scan at the maternal units of Singapore's two major public hospitals (KK Women's and Children's Hospital and National University Hospital) between June 2009 and September 2010 were recruited.
The pre-publication history for this paper can be accessed here: http://www.biomedcentral.com/1471-2393/14/193/prepub We acknowledge the three participating maternal units in Accra and Ghana Health Service for their cooperation and the midwives who shared their valuable experiences with us.
AG caused a significant reduction of sStx2 effects on the feto-maternal unit, but did not prevent premature delivery.
Treatment with 100 µg AG/g body wt 24 h before and 4 h after sStx2 injection caused a significant reduction of Stx2 effects on the feto-maternal unit (Figure 7E and F).
Concentrations of androgens in the feto-maternal unit throughout gestation are reviewed.
Afterwards, we highlight studies correlating androgen levels in the feto-maternal unit with adverse pregnancy outcomes.
During pregnancy, physiological regulatory set points (e.g., levels of insulin, cortisol, glucose, and leptin) continually change to accommodate the demands of the fetal-placental-maternal unit.
The Q2 group consisted of women who attended the feto-maternal unit and opted for an invasive genetic test following a screen-positive prenatal test for Down's syndrome or at the request of the pregnant woman due to maternal age.
Domoic acid, which is normally cleared rapidly by renal filtration in adult animals, is more toxic to animals in utero because of a longer residence time in the fetal-maternal unit and greater access to the fetal brain (Ramsdell and Zabka 2008).
