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Conclusion: Maternal substance abuse is associated with a significantly higher incidence of polyhydramnios and should be considered a possible etiologic factor in women with apparent idiopathic polyhydramnios.
Exposure to maternal substance use in pregnancy is believed to be a preventable hazard, and is therefore a main issue for public health concern and policy.
Accumulating evidence from both human and preclinical studies indicates maternal substance use during pregnancy can affect fetal development, birth weight and infant outcomes.
To determine the association of maternal substance use disorders (SUDs) during pregnancy with adverse neonatal outcomes and infant hospital re-admissions, observational stays, and emergency department utilization in the first year of life.
In the interest of improving child maltreatment prevention science, this longitudinal, community based study of 499 mothers and their infants tested the hypothesis that mothers' childhood history of maltreatment would predict maternal substance use problems, which in turn would predict offspring victimization.
In many places, even if physicians discover women who are using, they don't know what kinds of treatment options are available, said Dr. Ira Chasnoff, a Chicago-based researcher on maternal substance abuse who helped set up the pilot programs.
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The projects covered asthma, cancer, heart disease, diabetes, HIV and sexually transmitted diseases, pain management, maternal health, substance abuse, senior health, and adolescent health.
The study controlled for family psychiatric history, maternal psychosis, substance use, socioeconomic status, neighborhood social characteristics and other factors, but it is an observational study that does not prove causation.
The diagnosis of FGR was made within the 32nd week of gestation and was ascribed to a probable placental cause after excluding other causes as infections, chromosomal abnormalities, genetic syndromes, maternal malnutrition, substance abuse, gross placental abnormalities and multiple fetuses.
These risk factors are associated with woman abuse, child abuse, postpartum depression and couple dysfunction, and the risk factors are further grouped into four categories: family factors, maternal factors, substance use and family violence.
During gestation the developing human fetus is exposed to a diverse range of potentially immune-stimulatory molecules including semi-allogeneic antigens from maternal cells1,2, substances from ingested amniotic fluid3,4, food antigens5, and microbes6.
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