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Maternal separation pups were housed in a separate room (31 - 33°C to prevent hypothermia) for the 3-hour separation period to prevent mother-infant ultrasonic communication [ 39], since this may also attenuate maternal separation effects [ 40].
Zioli F. Maternal separation produces long-lasting changes in cortisol and behavior in rhesus monkeys.
Maternal separation with early weaning: a rodent model providing novel insights into neglect associated developmental deficits.
Environmental Enrichment reverses the effects of maternal separation on stress reactivity.
Millstein, R. A. & Holmes, A. Effects of repeated maternal separation on anxiety- and depression-related phenotypes in different mouse strains.
Millstein RA, Holmes A. Effects of repeated maternal separation on anxiety- and depression-related phenotypes in different mouse strains.
Maternal separation (MS) is an animal paradigm designed to make early life stress.
Infants who cried in response to maternal separation had greater right frontal asymmetry compared with infants who did not cry during the preceding baseline period (68).
Millstein RA, Ralph RJ, Yang RJ, Holmes A. Effects of repeated maternal separation on prepulse inhibition of startle across inbred mouse strains.
Fifty-two male Sprague Dawley rats underwent maternal separation, and gene expression was studied using array technology.
The model was created in the early 1990s by Dr. Plotsky himself to bring consistency to the way maternal separation is studied.
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