Sentence examples for maternal methylation of from inspiring English sources

After adjusting for multiple comparisons, maternal methylation of p16 at position 4 significantly predicted methylation at the same position in umbilical cord blood (β = 0.43, p = <0.0001).

Maternal methylation of p53 was not a significant predictor of umbilical cord %5mC at any of the 4 CpG dinucleotides assayed (Figures 1J M).

Maternal methylation of LINE-1 and Alu significantly predicted umbilical cord %5mC in LINE-1 and Alu, respectively (Figure 1A and 1B: β = 0.63, p<0.0001; β = 0.28, p = 0.009).

FAM50B and GNAS1A were paternally expressed and were coupled with maternal methylation of corresponding DMRs.

Thus, an efficient maternal methylation of iAs leads to less arsenic excretion in breast milk.

Three (6%) had loss of maternal methylation of KCNQ1OT1 and none had tumors.

DNA methyltransferase-3-like (DNMT3-Like) lacks enzymatic activity but may be essential for the establishment of maternal methylation imprints and the appropriate expression of maternally imprinted genes.

This CpG Island shows a relatively uniform pattern of methylated maternal and unmethylated paternal alleles, with loss of maternal methylation in many patients with Beckwith-Wiedemann syndrome [ 24].

Thus, patients with mutations in ZFP57 (which is involved in the establishment and maintenance of genomic imprinting) presenting with prenatal growth failure and transient neonatal diabetes mellitus (TNDM, OMIM 601410) showed loss of maternal methylation at the PLAGL1 DMR and variable loss of maternal methylation at GRB10, PEG3, NESPAS and MEST[ 16].

In mice, absence of ZFP57 also results in defective establishment of maternal methylation at the imprinted Snrpn locus [3,5].

The KCNQ1OT1 transcript is paternally expressed, and biallelic expression of this transcript is caused by a loss of maternal methylation at the KvDMR, as occurs in BWS.