Sentence examples for maternal copy of from inspiring English sources

Their results indicate that the wild-type maternal copy of MYBPC3 probably provided the repair template, rather than the introduced copy.

The authors designed the repair template to encode the same amino acids as the wild-type maternal copy of the gene, but used some different nucleotides so that they could distinguish between repair using either the maternal copy of MYBPC3 or the introduced repair template.

Angelman syndrome (AS) is a neurological genetic disorder caused by loss of expression of the maternal copy of UBE3A in the brain.

Mitalipov adds that in further, unpublished experiments, his team has corrected mutations in a different gene responsible for hypertrophic cardiomyopathy, and that gene repair again occurred using the healthy maternal copy of the gene in those experiments.

Ma et al. report that 42 of 58 embryos tested (72.4%) did not have the MYBPC3 mutation, and their analysis suggests that the maternal copy of the gene is used as a template to guide the repair.

One maternal copy of sctt+ is sufficient to completely rescue germ cell migration (Figure. 1D).

HB11 would have more maternal copies of 19q13 and more paternal copies of 20q13.

Inheritance of two maternal copies of human chromosome 14q32.2 (Temple syndrome) causes severe foetal growth retardation and post-natal failure to thrive.

In the PWS region, the paternal copies of the genes are typically expressed while the maternal copies of these genes are silenced due to parent-of-origin-specific imprinting.

Due to the difficulty in separating two (paternal and maternal) copies of a chromosome, most published human genome sequences only provide genotype information, i.e., the mixed information of the underlying two haplotypes.

Reduced expression of DLK1 (most commonly due to maternal uniparental disomy: bearing two maternal copies of chromosome 14) also leads to a set of features, including infant postnatal growth reductions, that overlaps with those of Prader Willi syndrome (Cox et al. 2004; Crespi 2008), with comparable phenotypes also found in DLK1-knockout mice (Moon et al. 2002).