Laidlaw's filings with the Securities and Exchange Commission warn that any pension contributions "could have a materially adverse effect on the financial condition of Greyhound".
Unlikely but theoretically plausible scenarios could have the damage entering the realm of the costliest natural disasters of all time, and perhaps being large enough to have a materially negative effect on the nation's gross domestic product.
Led by JC Flowers, the group made a $25 billion offer for Sallie Mae in April, but says recent government legislation that reduces subsidies to student lenders has had a materially adverse effect on the deal.A consortium led by JPMorgan and which includes an Australian infrastructure fund won the auction of Britain's Southern Water in a deal worth £4.2 billion ($8.4 billion).
Additional adjustment for well-water arsenic or total urinary arsenic did not materially change the effect estimates (data not shown).
However, AF was not associated to these potential confounders and adjusting for these variables in the model did not materially change the effect sizes (data not shown).
Postnatal smoking, birth weight, parity, maternal alcohol use and maternal age were not included in the final models since they did not materially change the effect estimates.
There was no association in controls between age and genotype frequency for any of the SNPs, and adjusting for age did not materially alter the effect estimates and thus age was not included in the models (data not shown).
Models were assessed for age-group by sex interaction, but because inclusion of this interaction term did not materially change the effect size for any of the models, they were excluded from the final models.
In a recent study of 1,147 live births among nurses, controlling for parity, smoking, alcohol, coffee, multivitamin, and folic acid intake did not materially change the effect estimates for congenital anomalies [ 15].
