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Further research is then needed to answer all these questions including when to inject stem cells in DO and when to inject nanocomposite scaffolds and which material is optimal in inducing osteogenic differentiation in DO? Which growth factor and delivery system are the optimal one to be used with stem cells for osteogenic induction?
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The challenge now is in the materials — trying to figure out what materials are optimal, what materials are safe, what materials can meet the general requirements that we have in order to make better automobile batteries.
Calcium phosphate (CaP) materials are optimal candidate biomaterials for bone tissue engineering because of their bioactivity and biocompatibility.
The mix formula of this material was optimized, the solidified material with optimal mix formula (fly ash/steel slag = 1 1, phosphogypsum dosage = 2.5%) results in highest strength.
According to the blast effect in the concrete target, the charge with carbon composite material shell is optimal in matched impedance and detonation propagation.
The combination of high intrinsic molecular density silicon oxide (SiOx) and pinhole-free and stress releasing poly-para-xylylene (parylene-C) thin films creates a new composite material, which is optimal for hermetic and biocompatible packaging.
While extensive literature on scaffolds, hydrogels, and nanoparticles exists, there is currently no consensus as to which material is most optimal in repairing the lesioned spinal cord.
In a study utilizing three different expanded polytetrafluoroethylene membrane qualities with different porosities placed on denuded rat calvaria, it was observed that there was a porosity range within which osteogenesis beneath the membrane is optimal, and the material with the smallest internodal distance did not integrate well with the surrounding soft tissue [ 27].
In so doing, we provide evidence that the theoretical bounds for this combination of material properties are optimal.
The lattice truss materials may be optimal designed according to their stacking mode of struts and the critical relative density.
Therefore, ongoing investigations into and evaluations of alternative weight-bearing surfaces are critical if we are to identify materials that are optimal in terms of minimizing particle generation over time [ 15, 26].
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