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Studies in mice indicated that the material abnormalities in OI have a negative impact on bone material properties.
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Membrane traffic is required to supply growing dendrites with building material and hence, abnormalities in the production of required lipids might impede this process.
Finally, Rab11a BKO mice appeared normal and displayed no obvious abnormalities (supplementary material Figs S1 S3).
Results showed specific Isl1-Cre expression in mutants displaying the full spectrum of abnormalities (supplementary material Fig. S2C–E').
Five independent transgenic UAS -MEK RNAi lines were examined, and four lines rescued the Raf-mediated cardiac abnormalities (supplementary material Table S1 and data not shown), suggesting that Raf-dependent signals to MEK are necessary for Raf-mediated cardiac hypertrophy.
A Chinese study of reproductive toxicity of enriched uranium noted damage to genetic material, dominant lethality and skeletal abnormalities in fetal rats.
Using expression of the Hsa21 gene SH3BGR as an alternative marker of Hsa21-retaining cells in the myocardium, we found no obvious association between distribution of Hsa21-expressing cells at either E14.5 or E18.5 and the presence of morphological abnormalities (see Supplementary material online, Figure S1 ).
Low-temperature diffusion anomaly in iron-nickel alloy after multiple γ-α-γ transformations was similar to that described in literature on diffusion abnormalities in nanocrystalline materials obtained by gas condensation method, electrodeposition method, and intensive plastic deformation.
In addition, two of the libraries, including those from the shoot apex (library A1) and from the male inflorescences (M2), were derived from oil palm material that exhibited the mantled abnormality phenotype, [ 15, 16].
and characterization of the resulting naturally occurring abnormalities (defects) in the material.
Results: The extracellular matrix showed flocculent material and collagen fibrils with structural abnormalities and variation in diameter.
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