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Differences in NRS scores between the responders and non-responders before and after age and gender matching were calculated using the unpaired t-test.
Balance between mTIH group and non-mTIH group for each variable was evaluated by propensity score distributions and absolute standardized differences (ASD) before and after matching were calculated (Fig. 1).
Standardized differences tests (SDT) for each variable before and after matching were calculated.
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To verify the covariate balancing after the propensity score matching, the standardised difference before and after the application of the propensity score matching was calculated.
The significance values for motif matches were calculated via Pearson correlation coefficient in TOMTOM.
PAM distances between matches were calculated with variances using the Darwin PamEstimator routine.
The locations of Pfam matches were calculated in relative intervals (0 5%, 5 10% and so on), similar to the location of PTCs in genes, and matches spanning over several intervals were recorded once in each interval.
In Task v2, trial matches were calculated by averaging the midpoints between contiguous pairs of crossing values, with each midpoint weighted by the inverse of the step size between that pair of crossings.
Confidence intervals for e values from 20 randomly selected A. thaliana and soybean matches with 6, 8, 10, 12, 14, 16, 18 and 20 additional 7 bp matches were calculated using the SPSS statistical program (SPSS Inc., Chicago, Illinois) Synteny maps were prepared for Mapchart [ 24] presentation.
The process is repeated for each original polymer and the fraction of correct matches is calculated.
The percent of cells (locations) matched is calculated as a performance measure.
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