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Individualization of T1DM model parameters is done by matching the simulator output to T1DM self-monitoring data obtained from continuous glucose monitoring (CGM) device.
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For this case, we attempt to match the outputs of our simulator to the data reported for the following patient variables - PO2, PCO2, deadspace, shunt, mean and standard deviation of V̇ and Q, and ventilation-perfusion distribution across a number of ranges (see Table 2).
Using this approach, we are able to achieve extremely close matches between the simulator and a range of patient data including PaO2, PaCO2, pulmonary deadspace fraction, pulmonary shunt fraction, and ventilation/perfusion (V̇/Q) curves.
The correlation functions of such channel simulators match the correlation functions of measured channels accurately over a wide range determined by the length of the measured data.
The project appears in the Journal of Food Engineering and promises "A new fruit simulator engineered to closely match the thermal response of real fruit" and a system for "artificial fruit that can monitor fruit pulp thermal history throughout the entire cold chain".
The simulator uses a "rotating forced downdraft" technique that loosely matches the rear flank downdraft (RFD) phenomenon often emphasized as important to tornadogenesis.
The same properties that concluded with the proper history matching were employed to make a history matching for a simulator core sample (rectangular) that has the same capacity of the experimental core sample (63.3 cm3 and with a smaller simulator diameter, 2.925 cm).
We use COSI [ 5] that is the only population simulator, to the best of our knowledge, that provides the ARG as well as produces populations that match the the genetic landscape of the observed human populations.
In this research, a complete reservoir production history matching is performed using the simulator under consideration indicating a similar production behavior of simulator to that of the real reservoir.
FA and DM implemented the simulator and performed the simulations.
Also, most previous efforts to match physiological simulators to specific disease states have relied on manually manipulating the parameters in the simulator.
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CEO of Professional Science Editing for Scientists @ prosciediting.com