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Conditional logistic regression was used to examine the association between the XRCC1 polymorphisms and breast cancer in two models, one controlling for matching factors only and the other controlling for matching factors and other possible confounders.
Matching factors included age, year of incidence of the primary tumour and postsurgical axillary nodal status.
He says an overhauled version of the recommendation system is in the works — which will place even more weight on tech giants' social graphs, as well as considering core matching factors such as people's location and age.
Conditional and unconditional logistic regression adjusting for matching factors and multivariate covariates were used to estimate the relative risk (RR) and results were similar.
Computerized optimal matching was performed to minimize the total "distance" between cases and controls in terms of the sum of the absolute difference in the matching factors [24].
Because results remained virtually unchanged regardless of the model used, we present results from the conditional models adjusting for matching factors only.
This adjustment disregards matching and does not account for variability in ascertainment; bias could still arise if ascertainment probability is associated with the matching factors.
*Adjusted for matching factors only.
Matching factors included age and menopausal status.
*Model based on matching factors only.
aConditional logistic regression, conditioning on matching factors.
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