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The algorithm matches the sequence of expression levels for each gene against temporal patterns having one or two transitions between two expression levels.
The PM exactly matches the sequence of a standard genotype, whereas the MM differs from the PM by a single base substitution at the central, 13th position (Borevitz and Chory 2004; Hazen and Kay 2003; Zhu and Salmeron 2007).
In addition, an evolutionary tree constructed by the researchers suggests that the order in which the genes appeared matches the sequence of steps in the assembly of the flagellum.
The deposition of Aβ plaques is considered one hallmark in the pathogenesis of AD, and a hypothetical model of biomarker temporal evolution has been proposed that matches the sequence of molecular events proposed in the amyloid cascade hypothesis (Jack & Holtzman 2013).
One justification is that the T7/synergy loop of BtubA closely matches the sequence of β tubulin, including the residue E254, which is K in a tubulin.
The sequence for amphoterin matches the sequence of HMGB1, establishing HMGB1 as a membrane protein on certain cells [ 5, 6].
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A disadvantage of this strategy is that because it depends on protein sequence matches, the sequences lacking protein matches cannot be clustered.
Templates that cannot match the sequence are discarded before attempting any mapping of content.
If the COG did not match, the sequence was recorded as a homolog that failed the reciprocal check.
The sequence matched the sequence of ZBTB42 from the UCSC genome browser database.
The PLU5 primer matched the sequence with only a 1-basepair difference; the PLU6 primer matched the sequence with a 7-basepair difference.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com