Patients who underwent NAC + RC (n = 180) were matched to controls who underwent RC alone (n = 324) on the basis of pT and pN stage, margin status, and year of RC.
Of these, 30 AI patients were matched to controls for age and sex.
Patients with AI were matched to controls for age and sex using the Optimal Matching method from the MatchIt package of R statistics [21].
Conditional logistic regression was used to model the effect of social status on injury risk; cases were matched to controls consisting of coworkers present on the floor, shift, and date of the injury event.
Within each center, DAA-treated patients will be matched to controls treated within 24 months of each other taking into account age, APACHE II, cardiovascular, respiratory, renal, and hematologic dysfunction, mechanical ventilation status, medical/surgical status, and infection site.
First, to control for differences in standard of care among centers and over time, DAA-treated patients will be matched to controls (DAA-free patients) enrolled within 2 years in the same cohort.
Patients with severe sepsis at high risk of death, who received DrotAA or not, with DNA available were included and matched to controls adjusting for age, APACHE II or SAPS II, organ dysfunction, ventilation, medical/surgical status, infection site, and propensity score (probability that a patient would have received DrotAA given their baseline characteristics).
Cases were not perfectly matched to controls because a few subjects could not be genotyped with this platform, but genotype call rates did not differ between cases and controls.
In a study of 260 ESRD patients matched to controls, the time from diagnosis with renal disease to onset of ESRD was shorter for patients homozygous for tryptophan (Trp) at the glycine to tryptophan (G460W) polymorphism versus those homozygous for glycine (Gly) [43].
Patients receiving DrotAA were matched to controls.
The patients were frequency matched to controls on age.
