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Subjects interested in participation were invited if they matched the participating patients with respect to age, gender and educational attainment.
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Table 1 shows the characteristics used to match the participating hospitals in according pairs.
For any match found, the participating pDNA sequences are translated back into protein sequences, and the corresponding protein alignment is calculated so as to determine statistical significance.
All clinics caring for 8 18 years old children with HIV infection in Sweden were asked to invite patients who matched the inclusion criteria to participate in the study.
Only injuries incurred during match play at the participating clubs were recorded and therefore absences from match play due to illness or injuries incurred through any other activity (including rugby training) were not included.
Most importantly, the overall bleeding rates improved significantly more at the intervention sites after prospective risk stratification than was observed at other matched hospitals participating in the NCDR registry (reduction in odds of bleeding at intervention sites 44% v 9% at control sites).
In addition to these sociodemographics, the distribution of the type of practice among participating GPs matched the national distribution [ 28]: 27% worked in a single handed practice (vs. 27% nationally), 30.2% worked in a duo-practice (31% nationally) and the remainder worked in practices comprising > 2 GPs.
However only 36% of the matched controls participated in the study, suggesting a possible selection bias.
For the 87 case days, there were 209 control days in which controls were matched to participating cases.
A similar bias is present in the MPP cohort despite prospective population-based design, as DNA samples were acquired from only ∼40% of cases and matched controls participating in a follow-up visit.
We note also that the evacuees' participation at follow-up was not significantly associated with whether the matched classmates participated (McNemar's test χ2 = 0.2, df = 1, p > 0.05, for 300 evacuee-classmate pairs).
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