Sentence examples for matched primary carcinomas from inspiring English sources

The latter comparison included seven liver metastases and their matched primary carcinomas (P<0.001) from the same patient.

Furthermore, FasL is more frequently expressed in colorectal liver metastases than in matched primary carcinomas (Mann et al, 1998).

Since we have shown that the 21/40 tested tumor suppressor genes show less methylation in metastases with respect to their matched primary carcinomas, methylation is probably not an epigenetic factor that could be used for therapy against metastatic tumor spread.

However, the mutations were not metastasis-specific per se as they were present in the matched primary carcinoma of the same patients, and there is no evidence that the mutations observed endowed these genes with metastagenic activity.

To our knowledge, our study is the first that compared promoter methylation in a large group of multiple localizations of distant human breast cancer metastases to their matched primary breast carcinomas and we tried to apply the "reporting recommendations for tumor markers" (REMARK criteria) as adequately as possible [ 21].

Primary and metastatic lesions from 54 and 40 patients with advanced ovarian carcinoma, respectively (including matched primary and metastatic lesions from 30 patients) were evaluated for nuclear accumulation of p53 (clone BP53-12-1) and cytoplasmembranousmbranous immunostaining of p185 erbB-2 (clone 3B5) by immunohistochemistry.

These included 9 pairs of matched primary and recurrent high-grade ovarian serous carcinoma ascites cell pellets (Table S1).

Increased β1-integrin was detected in metastasis (MT) breast carcinoma specimens compared with their matched primary tumors (PTs).

Similarly, a tissue microarray (TMA) study showed a higher EIF5A2 protein expression in metastatic hepatocellular carcinoma (HCC) tumours compared with their matched primary HCC.

Assessment of positivity or negativity for CD44 and CD133 was performed semiquantitatively from immunohistochemically stained sections of matched primary and secondary tumor samples from patients with colorectal carcinoma and either synchronous or metachronous liver metastasis.

Moreover, in breast carcinoma EpCAM has been reported to be upregulated in large metastases as compared with the matched primary tumor [ 9].