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The trends observed previously were even more pronounced in matched pair samples.
To identify additional genetic alterations related to poor prognosis, a comprehensive genomic analysis using matched pair samples of onset and relapse might be useful.
We examined whether there was a difference in the main source of information (clinicians versus other sources in Table 1) between physical, developmental manifestations, and psychiatric manifestations (McNemar's test for matched pair samples, using exact binomial probability calculations, 2-tailed p; http://www.vassarstats.net/propcorr.html).net/propcorr.html
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We used a matched pair sampling design to control for confounding variance.
Each sample's tryptic peptides were uniquely mass tagged and mixed with their matched pair sample.
Figure 2 showed the IBS of 2 matched pairs (samples 76629543 and 2000619) in NGS across the genome.
For data that followed a normal distribution, unpaired and paired student T-tests were performed to assess differences between two independent groups or matched paired samples, respectively.
The data, including those of the 10 matched paired samples, are shown in Figure 4. Examples of CD68+ and infiltrating macrophages as well as CCR2-expressing tumours are shown in Figure 5.
Of the 150 matched (paired) samples, AFBs were detected in: 44 (29%) of the ZN smears examined under light microscope; 60 (40%) of the AR smears examined with FM; 49 (33%) of the AR smears examined with CY; and 64 (44%) AR smears examined with PiLED fluorescence microscopes.
Perou et al examined 40 breast tumours, and 20 matched pairs of samples before and after doxorubicin treatment in their study; tumour samples were grossly dissected.
From 102 matched pairs of samples (Additional file 5), we found the expression levels of miR-96, miR-182 and miR-183 in tumor samples were increased 8.4 (± 1.1 -fold, 4.2 ± (1.1 -fold and 7.5 ± (1.1)-fold respectively compared to the matched normal samples.
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