Sentence examples for matched normal samples from inspiring English sources

Tumour and matched normal samples were included in this analysis to exclude germline variants.

Somatic variants were identified after deducting the normal/germline variants observed in the matched normal samples from those observed in the tumor samples.

Sequencing of PIK3CA exons 9, 20 was done by PCR amplification and direct sequencing of both strands for all CRC cases and their matched normal samples as previously described (Saal et al., 2005; Abubaker et al., 2007).

The average number of reads per targeted base with WGS was 29.0 ± 5.3 for the six tumor specimens and 35.0 ± 4.6 for the matched normal samples, with over 93% of bases represented by at least 10 reads (Supplementary Table 3).

To validate miR-21 ISH results we performed miR-21 qRT-PCR analysis in a series of 10 AVCs and their matched normal samples.

Two additional matched normal samples were altered at the locus, but their respective tumors were not.

The tagged 4 k Mbr phage-Ab library was panned on primary human epithelial cells derived from tumor or matched normal samples as described above.

Four models are considered in explaining the read counts in both tumor and matched normal samples.

Using tumor and matched normal samples, we systematically identified genes with tumor-specific intron retentions.

Tumour and matched normal samples were snap-frozen and stored at − 80 °C until DNA preparation.

We obtained high coverage sequencing data (30 120x) for tumor and matched normal samples (Table 1).