Sentence examples for matched normal lung from inspiring English sources
Paired-samples t-test was used to evaluate the difference between protein levels of Cyr61, CTGF, or WISP-1 in cancer samples compared with matched normal lung tissues.
Expression of Cyr61 and CTGF in primary lung cancers was significantly lower than in matched normal lung tissues (P<0.001 and P = 0.016, respectively).
Total RNA was extracted from fresh-frozen NSCLC specimens and matched normal lung tissues by TRIzol reagent (Life Technologies , Inc. according to the manufacturer's protocol.
To explore the correlation between expression of CCN genes and NSCLC, we used real-time PCR and immunohistochemistry to evaluate the mRNA and protein levels of these three genes in NSCLC and their matched normal lung tissues.
Previously we reported that the level of the mouse wild-type p53 protein was reduced in 10 of 10 tumor samples as compared to matched normal lung tissue of the transgenic mouse [57].
In our experiments, we found that the level of expression of CTGF in NSCLCs was lower than in the matched normal lung samples, implying its potential tumor-suppressing function.
A previous report showed increased levels of activated ERK1/2 in a very reduced number of lung cancer tissues when compared to matching normal lung (Hoshino et al, 1999).
DLEC1 methylation was cancer-specific, as it was only rarely detected in matching normal lung tissue, and was strongly associated with stage II tumours and the spread of cancer to regional lymph nodes (P<0.0001).
Resected tumor and matched normal adjacent lung specimens were obtained with patients' consent from the Memorial Sloan-Kettering Cancer Center MSKCCC) lung cancer tissue bank via a protocol approved by the Institutional Review Board (protocol #92-055).
In groups 2 and 3, samples from patients with cancers, matched normals, benign lung disease and control sera for the assay were interspersed in the order samples were assayed so that any batch effects would be spread over all sample types.
Peptides from 8 tumors and 8 tumor-matched normal lung tissue were extracted and labeled with 8-channel iTRAQ reagents.
