Sentence examples for matched normal epithelium from inspiring English sources

Furthermore, all 14 PA samples obtained from patients that progressed to CaExPA expressed lower levels of WIF1 than their matched normal epithelium (P<0.001).

Analysis of matched normal epithelium from each individual with SCC revealed that each was heterozygous for this polymorphism in the germline.

Fresh tissue samples (tumor vs. matched normal epithelium) were subjected to whole transcriptome analysis and the results validated on the same cohort with RT quantitative real‐time PCR.

The analysis revealed that 82% of patients, who have methylated PMEPA1 gene, have lower PMEPA1 expression in tumors compared with matched normal epithelium (Fig. 2B).

The obtained values in tumours (T) were compared to those in matched normal epithelium (N) and T/N ratios were calculated for each mRNA from each patient's tissue samples.

Cancer tissue contained only one sequence-altered allele of the gene ATP50, which was present heterozygously alongside the wild-type allele in matching normal epithelium.

Fresh-frozen tumour tissue was available from 40 cases of vulval SCC, each with matched normal vulval epithelium.

Cervical carcinomas, cervical intraepithelial neoplasia (CIN) tissues and matched, normal cervical epithelium were obtained at hysterectomy or cone biopsy.

Batch P (numbered 3108 3323) were the 22 discovery cohort oesophageal adenocarcinomas with matched normal squamous epithelium or blood as described [ 22].

All sequence alterations were detected in both colorectal cancer tissue and matched normal colonic epithelium, with the exception of an alteration in the gene ATP50 (NM_001697), which manifested a unique expression mechanism (Fig. 1).

For example, a mouse transcriptomics study investigating gene expression in MMTV-neu tumors found that PADI2 expression was upregulated ~2-fold in hyperplastic, and ~4-fold in primary neu-tumors, when compared to matched normal mammary epithelium [ 12].