Sentence examples for matched normal cells from inspiring English sources

As reported in Figure 3a, all three phage-Abs differentially bound tumor cells, whereas the matched normal cells and clone HL60-D3-232 retained its binding specificity when formatted as IgG (Mbr-4; Figure 3b).

Genomic DNA from each of the 7 melanoma and their matched normal cells (either EBV cell line or PBL); as well as two control melanocytes were genotyped on the Illumina Infinium Human1M-Duo arrays.

To capture these abnormalities, DNA microarrays, which permit the simultaneous measurement of expression levels of tens of thousands of genes, have been increasingly utilized to characterize the global gene-expression profiles of tumor cells and matched normal cells of the same origin.

All these data show that the in vitro proliferative potential of tumour-associated fibroblasts is higher than that of their matched normal cells.

Unlike other tumor biomarkers, the specificity of somatic alterations is derived from the fact that mutations are present in the genome(s) of tumor cells but not in the genome of matched normal cells.

27 LIMK2 gene expression was also significantly lower in lamina proprial or epithelial adenomas and carcinomas relative to matched normal cells that had been separated by laser capture microdissection from normal, adenoma and carcinoma samples 28 (figure 1F).

The same selectivity was observed for a variety of cancer and matched normal cell lines.

Remarkably, in all the analysed pairs of normal vs tumour stromal cell cultures, the proliferation capacity of the tumour stroma was higher than that of matched normal cell culture (Table 2, P=0.003, paired t-test).

The broad tumor cell specificity of the synthesized disaccharide dye conjugates was validated by the similarity in their uptake profiles in spite of the variation in their uptake efficiency for the different cancer and matched normal cell lines studied.

The DNA samples from mammary carcinoma cell lines HCC-18066, HCC-11433, HCC-1428 and HCC-1937) and matched normal cell lines were received from Dr R Parson of Columbia University, New York, USA.

We applied the method to predict CNAs in mate-pair datasets for the melanoma cell line COLO-829 and matched normal cell line COLO-829BL (Pleasance et al., 2010), a paired-end dataset for the small-cell lung cancer cell line NCI-H2171 (Campbell et al., 2008) and a single-end dataset for the breast cancer cell line HCC1143 (Chiang et al., 2009).