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Additionally, the samples were not matched for potential differences such as handedness, and even differed in age which itself has an effect on brain structure.
Fourth, the two groups of patients studied were not matched for potential confounders such as age, duration, and type of diabetes, A1C, smoking habits, and cardiovascular risk factors.
Our study is not immune to such potential bias and although we matched for potential confounding variables, we had limited possibilities to adjust for residual confounding.
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Standardised differences for the participant characteristics included in the propensity score were all <0.1, indicating that the two cohorts were well matched for measurable potential confounders (table 3).
This design was chosen to minimise ascertainment bias, facilitate identification of controls that could be matched for all potential confounding factors and ensure accurate standardised and high quality data collection.
We matched them for potential influencing characteristics and required the same duration of illness and minimum number of previous episodes.
Only 10 studies matched for three or more potential confounding factors (age, genetic risk, geographical location, and sampling time).
Fourth, our control group was not matched for rheumatic disorders, since a potential deprivation of steroids would have been largely unethical.
In order to determine reliable data regarding the clinical efficacy of CaPE, future trials should also match groups for potential confounding factors such as concomitant pharmacological treatment, duration of illness, and type of disorder (i.e., type I or type II).
In addition to his role as the coach of the men's national team, he is now responsible for supervising and expanding the country's infrastructure for developing élite soccer talent: selecting coaches for the national teams, helping design the curricula for the coaches of travelling youth clubs, and overseeing the scouting of amateur matches for potential talent.
In May 2015, Fifa introduced an Anti-Discrimination Monitoring System which will assess 850 high-risk matches for potential discriminatory incidents during the 2018 World Cup qualifiers and friendlies.
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