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One possibility, especially to address issue 2 above is to determine if we can identify a demographically matched data set by pooling data from the ASR data sets and the other IDE control datasets.
In the first step, we performed a time-series analysis on the matched data set for each community using Poisson regression.
Data loss due to students' missing the pretest, the posttest, or using faulty or no identification yielded a matched data set of 394 sets of quizzes.
To control for the difference in group size, we used a subsampling approach that repeatedly selects a random subgroup of patients, matched in size with the control group, and re-computed statistics for this smaller, matched data set (Supplementary material and Supplementary Table 9).
With a matched data set, which addressed the fact that fewer data points were available for NN analysis (5,210 instead of 10,444), the performance of our post-1999 model performance remained high (cross-validation R = 0.76) and was comparable with that across all observations.
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These are the variables that are used in the matching methods to generate the matched data sets.
Inferences from a meta-analysis of matched data sets were presented in Newton & Wernisch [ 7] for a few potential regulators whereas the present analysis makes available the results for all potential regulators in the matched data sets.
In the next section, we show how the multivariate permutation approach can be extended to the survival matched data setting.
Both methods, histology and ELISpot analysis gained comparable results (Fig. 1c) and matched data sets from NZB/W mice significantly correlated (Fig. 1d).
By estimating the number of false matches (as above) in matched data sets derived using different strategies, the trade-off between false matches and matches missed due to inconsistent data can be examined.
Clustered Image Maps (CIM), also called 'clustered correlation' or 'heatmaps' were first introduced by [ 11, 28, 29] to represent either the expression value of a single data set, or the Pearson correlation between two matched data sets [ 11, 30].
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