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In this study, cases and matched controls where identified through systematic analysis on PubMed and 68 comparisons from 60 different studies were made.
A similar relationship was observed in the plasma levels of miR-454 of sickle cell anaemia (SCA) patients compared with healthy matched controls, where elevated ET-1 and PAI-1 levels are observed.
A sensitivity analysis will be run on the subgroup of cases and their matched controls where the case diagnosis is supported by thrombolytic prescriptions in the 6 weeks before or after the VTE diagnosis.
We also analysed length of stay and mortality in cases (patients experiencing the particular safety event measured by an indicator) and matched controls (where such an event did not occur) for each indicator except death in low mortality health resource groups to establish whether or not the results indicated that an adverse event had occurred among cases.
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Log(2)ratios were created by dividing the median of the values of each probe set by the median of the time matched control where only probesets were selected that contained a "present" flag.
In the current study, the researchers sampled the blood of 50 middle-aged men and women from Libby and 50 matched controls from Missoula, where there is no known asbestos exposure.
In a matched control experiment, where flies were subjected to sham infection, none of the sham infected flies died.
These cell cycle regulatory elements have facilitated the ability of YE-PC8 viruses to mediate transgene expression in accordance with the proliferation status of the host cells, but this was not observed in matched control virus where the luciferase reporter gene was placed under the regulation of the ubiquitous CMV promoter.
Though alarming, the low percentage of subjects at or below this healthy %fat target probably provides a more realistic assessment of %fat and FMI levels versus comparing subjects to age-matched controls, where by definition 50% of subjects would appear "normal".
Our study also demonstrated that WMH is higher and BPF lower in our patients compared to age-matched controls, where 69% had no signs of WMH.
Our data are in accordance with a recent study comparing the metabolome of plasma and CSF of AD patients and cognitively normal age-matched controls, where disturbances in multiple pathways related to energy metabolism and mitochondrial function were identified [ 36].
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com