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Although changes in mRNA expression were observed during development for Cx30 only, acute hypoxia did not result in changes in mRNA expression of all these Cxs when compared to age matched controls suggesting that acute hypoxia induced posttranslational changes in protein expression.
Some studies have also shown that intermediate level practitioners of mindfulness have thicker insula compared to matched controls, suggesting that mindfulness training significantly changes the brain in ways that improve empathy.
Acylcarnitine levels were increased in neonates with both perinatal asphyxia and HIE relative to matched controls, suggesting a defect in fatty acid oxidation, resulting in their accumulation and release into circulation [ 62].
Adult women with TS have higher 2 h glucose levels and reduced measures of insulin secretion (HOMA-b and first phase insulin release) when compared to age matched controls, suggesting impaired insulin secretion [11].
A previous open study has reported the expression of OCT-6 protein in the frontal and temporal lobes of patients diagnosed with schizophrenia but its absence from matched controls, suggesting it may be a putative biological marker for schizophrenia [ 6].
Our results showed higher frequency of APOE ε2 allele and predominance of ε2/ ε3 genotype in the psoriasis patients in comparison with matched controls suggesting that allele ε2 carriers are at a higher risk of developing psoriasis.
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The negative geotaxis assay revealed significant impairment in climbing ability in aging per flies relative to age-matched controls suggesting that lack of per impairs physical performance during aging.
In addition, 14- to 16-month-old pericyte-deficient mice have a 20- to 25-fold plasma-derived immunoglobulin buildup in the cortex and hippocampus compared to age-matched controls suggesting blood brain barrier breakdown (Bell et al, 2010).
In contrast, one study observed an increased CSP in MD patients compared with age-matched controls, suggesting increased cortical inhibition [ 44].
The plaques in the AD brains are colocalized with the advanced glycation endproducts (AGEs), and the plaque-enriched fractions contain approximately threefold higher AGE adducts than that of the age-matched controls, suggesting that A β may be glycated.
The levels of (SH 2 Trx-ASK1 are more abundant in young and old dwarf mice compared to their age-matched controls suggesting that the levels of this complex may play a role in their resistance to oxidative stress.
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